Rubidox

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RUBIDOX

Doxorubicin HCl

Class

Anthracyclines

MOA

Intercalation inhibits nucleotide replication and the action of DNA and RNA polymerases. The interaction
of doxorubicin with topoisomerase II to form DNA-cleavable complexes appears to be an important
mechanism of doxorubicin hydrochloride cytocidal activity.

Indications

Adjuvant breast cancer
Acute lymphoblastic leukemia
Acute myeloblastic leukemia
Hodgkin lymphoma
Non-Hodgkin lymphoma (NHL)
Metastatic breast cancer
Metastatic Wilms’ tumor
Metastatic neuroblastoma

Metastatic bone sarcoma
Metastatic ovarian carcinoma
Metastatic transitional cell bladder carcinoma
Metastatic thyroid carcinoma
Metastatic gastric carcinoma
Metastatic bronchogenic carcinoma
Metastatic soft tissue sarcoma

Pack Size
1’s
Storage
2-8 °C
Available Strength
10mg/5ml Injection
50mg/25ml Injection