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LIVE LIFE Everyday
Doxorubicin HCl
Class
Anthracyclines
MOA
Intercalation inhibits nucleotide replication and the action of DNA and RNA polymerases. The interaction
of doxorubicin with topoisomerase II to form DNA-cleavable complexes appears to be an important
mechanism of doxorubicin hydrochloride cytocidal activity.
of doxorubicin with topoisomerase II to form DNA-cleavable complexes appears to be an important
mechanism of doxorubicin hydrochloride cytocidal activity.
Indications
- Adjuvant breast cancer
- Acute lymphoblastic leukemia
- Acute myeloblastic leukemia
- Hodgkin lymphoma
- Non-Hodgkin lymphoma (NHL)
- Metastatic breast cancer
- Metastatic Wilms’ tumor
- Metastatic neuroblastoma
- Metastatic bone sarcoma
- Metastatic ovarian carcinoma
- Metastatic transitional cell bladder carcinoma
- Metastatic thyroid carcinoma
- Metastatic gastric carcinoma
- Metastatic bronchogenic carcinoma
- Metastatic soft tissue sarcoma
Pack Size
1’s
Storage
2-8 °C
Available Strength
10mg/5ml Injection
50mg/25ml Injection