Bisphosphonate

Zoledronic acid is a type of bisphosphonate drug that works by binding to the bone mineral and inhibiting the activity of osteoclasts, which are cells that break down bone tissue. By blocking osteoclast activity, zoledronic acid prevents bone loss and can help to increase bone density in patients with osteoporosis or other conditions that cause bone loss.
Zoledronic acid has also been shown to have anti-tumor activity in some types of cancer. It may inhibit the growth and spread of cancer cells by blocking the production of certain proteins that are necessary for tumor growth and survival.
Overall, the pharmacologic action of zoledronic acid is to inhibit bone resorption and promote bone density, which can help to prevent fractures and other complications associated with bone loss.